Nuclear localization of aldosterone in rat brain cells assessed by autoradiography

Nuclear localization of aldosterone in rat brain cells assessed by autoradiography

Autoradiographic studies with 3H aldosterone demonstrate nuclear concentration of hormone in neurons of the hippocampus, septum, allocortical regions and brain stem reticular formation and motor nuclei of cranial nerves and in the meninges. The results suggest that mineralocorticoids have wide rangi...

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Veröffentlicht in:Experientia 1979-09, Vol.35 (9), p.1240-1241
Hauptverfasser: Birmingham, M K, Stumpf, W E, Sar, M
Format: Artikel
Sprache:eng
Schlagworte:
Adrenalectomy
Aldosterone - metabolism
Animals
Autoradiography
Brain - metabolism
Cell Nucleus - metabolism
Female
Neurons - metabolism
Rats
Tissue Distribution
Tritium
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Zusammenfassung:Autoradiographic studies with 3H aldosterone demonstrate nuclear concentration of hormone in neurons of the hippocampus, septum, allocortical regions and brain stem reticular formation and motor nuclei of cranial nerves and in the meninges. The results suggest that mineralocorticoids have wide ranging effects on different parts of the central nervous system.
ISSN:0014-4754
1420-9071
DOI:10.1007/BF01963313