Suppression of intrinsic B-cell function in dengue -infected mice

Mice infected with Dengue virus show a depressed immune response to lipopolysaccharide (LPS), a helper T-cell-independent antigen, when LPS was administered on day 0, 6 and 12 post infection. Mice injected with inactivated virus failed to show immunosuppression.

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Veröffentlicht in:Experientia 1979-11, Vol.35 (11), p.1518-1519
Hauptverfasser: Nagarkatti, M, Nagarkatti, P.S
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creator Nagarkatti, M
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description Mice infected with Dengue virus show a depressed immune response to lipopolysaccharide (LPS), a helper T-cell-independent antigen, when LPS was administered on day 0, 6 and 12 post infection. Mice injected with inactivated virus failed to show immunosuppression.
doi_str_mv 10.1007/BF01962820
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source MEDLINE; Springer Nature - Complete Springer Journals
subjects Animals
Antibody Formation
B-Lymphocytes - immunology
Dengue Virus - immunology
Immunosuppression
Kinetics
Lipopolysaccharides - immunology
Mice
viruses
title Suppression of intrinsic B-cell function in dengue -infected mice
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