Suppression of intrinsic B-cell function in dengue -infected mice

Suppression of intrinsic B-cell function in dengue -infected mice

Mice infected with Dengue virus show a depressed immune response to lipopolysaccharide (LPS), a helper T-cell-independent antigen, when LPS was administered on day 0, 6 and 12 post infection. Mice injected with inactivated virus failed to show immunosuppression.

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Bibliographische Detailangaben
Veröffentlicht in:Experientia 1979-11, Vol.35 (11), p.1518-1519
Hauptverfasser: Nagarkatti, M, Nagarkatti, P.S
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Antibody Formation
B-Lymphocytes - immunology
Dengue Virus - immunology
Immunosuppression
Kinetics
Lipopolysaccharides - immunology
Mice
viruses
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Beschreibung
Zusammenfassung:Mice infected with Dengue virus show a depressed immune response to lipopolysaccharide (LPS), a helper T-cell-independent antigen, when LPS was administered on day 0, 6 and 12 post infection. Mice injected with inactivated virus failed to show immunosuppression.
ISSN:0014-4754
1420-9071
DOI:10.1007/BF01962820