Discovery of novel avermectins with unprecedented insecticidal activity

A new class of insecticidal and antiparasitic agents, 4"-amino-4"-deoxy avermectins, has been developed by chemical modification of avermectin B sub(1). The most effective of these compounds are 1500-fold more potent than avermectin B sub(1) (abamectin) against the beet armyworm Spodoptera...

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Veröffentlicht in:Experientia 1989-03, Vol.45 (3), p.315-316
Hauptverfasser: Mrozik, H, Eskola, P, Linn, B.O, Lusi, A, Shih, T.L, Tischler, M, Waksmunski, F.S, Wyvratt, M.J, Hilton, N.J, Anderson, T.E
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Sprache:eng
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Zusammenfassung:A new class of insecticidal and antiparasitic agents, 4"-amino-4"-deoxy avermectins, has been developed by chemical modification of avermectin B sub(1). The most effective of these compounds are 1500-fold more potent than avermectin B sub(1) (abamectin) against the beet armyworm Spodoptera exigua) and show similar potency against other lepidopteran larvae.
ISSN:0014-4754
1420-9071
DOI:10.1007/BF01951823