Liver function during chronic renal failure in rabbits

In rabbits with chronic renal insufficiency the prothrombin index was increased by 25% and the alanine aminotransferase activity decreased by 20%; the results of other routine tests of hepatic function were not affected. The galactose elimination capacity was decreased by 12%, whereas the body clear...

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Veröffentlicht in:	Experientia 1984-11, Vol.40 (11), p.1255-1256
Hauptverfasser:	TVEDEGAARD, E, POULSEN, H. E, VILSTRUP, H, THOMSEN, H. K
Format:	Artikel
Sprache:	eng
Schlagworte:	Alanine Transaminase - metabolism Alkaline Phosphatase - metabolism Animals Biological and medical sciences Galactose - metabolism Kidney Failure, Chronic - pathology Kidney Failure, Chronic - physiopathology Liver - pathology Liver - physiopathology Male Medical sciences Nephrology. Urinary tract diseases Nephropathies. Renovascular diseases. Renal failure Prothrombin Time Rabbits Renal failure
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Beschreibung
Zusammenfassung:	In rabbits with chronic renal insufficiency the prothrombin index was increased by 25% and the alanine aminotransferase activity decreased by 20%; the results of other routine tests of hepatic function were not affected. The galactose elimination capacity was decreased by 12%, whereas the body clearance of antipyrine was unchanged. No change in hepatocytic structure was found.
ISSN:	0014-4754 1420-9071
DOI:	10.1007/BF01946660