Persistent inverse maternal effect on corticosterone production in vitro

Persistent inverse maternal effect on corticosterone production in vitro

Adrenal cells from C57BL/Tb mice produced more steroid than those from DBA/2J mice. Reciprocal differences between both backcross and F1 hybrids showed a persistent maternal effect. Mothers with high output produce offspring with reduced hormone production when adult. Corticosterone output thus depe...

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Veröffentlicht in:Experientia 1984-09, Vol.40 (9), p.1000-1001
Hauptverfasser: WOOD, P. R. W, SHIRE, J. G. M
Format: Artikel
Sprache:eng
Schlagworte:
adrenal gland
Adrenal Glands - metabolism
Adrenals. Interrenals
Adrenocortical hormones. Regulation
Animals
Biological and medical sciences
corticosterone
Corticosterone - biosynthesis
Female
Fundamental and applied biological sciences. Psychology
Genotype
Hybridization, Genetic
inbreeding
Male
maternal effects
Mice
Mice, Inbred C57BL
Mice, Inbred DBA
Phenotype
Vertebrates: endocrinology
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Zusammenfassung:Adrenal cells from C57BL/Tb mice produced more steroid than those from DBA/2J mice. Reciprocal differences between both backcross and F1 hybrids showed a persistent maternal effect. Mothers with high output produce offspring with reduced hormone production when adult. Corticosterone output thus depends on maternal phenotype as well as on the genotype of the isolated cells.
ISSN:0014-4754
1420-9071
DOI:10.1007/BF01946479