Uptake of noradrenaline in high altitude native's heart

Uptake of noradrenaline in high altitude native's heart

Uptake of 3H-noradrenaline by the heart was studied with sections of isolated atria obtained from high or lowlanders. In native highlanders, affinity for 3H-noradrenaline by human atria is more significant than in lowlanders. Furthermore, the Michaelis Menten constant is lower in high altitude nativ...

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Veröffentlicht in:Experientia 1977-06, Vol.33 (6), p.739-740
Hauptverfasser: Rapin, J R, Coudert, J, Drouet, L, Durand, J, Cohen, Y
Format: Artikel
Sprache:eng
Schlagworte:
Adaptation, Physiological
Adult
Altitude
Biological Transport
Humans
In Vitro Techniques
Kinetics
Middle Aged
Myocardium - metabolism
Norepinephrine - metabolism
Space life sciences
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Zusammenfassung:Uptake of 3H-noradrenaline by the heart was studied with sections of isolated atria obtained from high or lowlanders. In native highlanders, affinity for 3H-noradrenaline by human atria is more significant than in lowlanders. Furthermore, the Michaelis Menten constant is lower in high altitude native's heart.
ISSN:0014-4754
1420-9071
DOI:10.1007/BF01944162