Transport of the synthetic peptide DSIP through the blood-brain barrier in rabbit

The synthetic delta sleep inducing peptide (DSIP) passes the blood-brain barrier, since i.v. injection in free moving rabbits (30 nmoles/kg) significantly increases the cortical delta activity and decreases the motor activity during 5 h.

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Bibliographische Detailangaben
Veröffentlicht in:	Experientia 1977-12, Vol.33 (12), p.1609-1610
Hauptverfasser:	Monnier, M, Dudler, L, Gächter, R, Schoenenberger, G A
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Behavior, Animal - drug effects Blood-Brain Barrier Electroencephalography Motor Activity - drug effects Oligopeptides - metabolism Oligopeptides - pharmacology Rabbits
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Beschreibung
Zusammenfassung:	The synthetic delta sleep inducing peptide (DSIP) passes the blood-brain barrier, since i.v. injection in free moving rabbits (30 nmoles/kg) significantly increases the cortical delta activity and decreases the motor activity during 5 h.
ISSN:	0014-4754 1420-9071
DOI:	10.1007/BF01934026