Effect of an antiandrogen on the lymphoid system

A side-effect of the administration of cyproterone acetate, an antiandrogenic steroid, to newborn, juvenile or adult male mice (in doses comparable to those used clinically) was found in a marked reduction of the white pulp of the spleen and reduced weight or even absence of the thymus.

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Bibliographische Detailangaben
Veröffentlicht in:	Experientia 1976-09, Vol.32 (9), p.1202-1203
Hauptverfasser:	Vojtísková, M, Polácková, M, Viklický, V
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Factors Animals Animals, Newborn Cyproterone - pharmacology Male Mice Organ Size - drug effects Spermatogenesis - drug effects Spleen - drug effects Testis - drug effects Thymus Gland - drug effects
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Beschreibung
Zusammenfassung:	A side-effect of the administration of cyproterone acetate, an antiandrogenic steroid, to newborn, juvenile or adult male mice (in doses comparable to those used clinically) was found in a marked reduction of the white pulp of the spleen and reduced weight or even absence of the thymus.
ISSN:	0014-4754 1420-9071
DOI:	10.1007/BF01927627