Inhibition of protein synthesis in ischaemic liver from phenobarbitone-treated rat
Both ribosomal factors and cytosolic inhibitors are involved in the reduction of the rate of protein synthesis which occurs in the ischaemic hepatocyte from control and phenobarbitone-treated livers. Of these 2 factors it is the latter which seems to play a major role in determining the irreversible...
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Veröffentlicht in: | Experientia 1979-01, Vol.35 (1), p.86-88 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Both ribosomal factors and cytosolic inhibitors are involved in the reduction of the rate of protein synthesis which occurs in the ischaemic hepatocyte from control and phenobarbitone-treated livers. Of these 2 factors it is the latter which seems to play a major role in determining the irreversible impairment of protein synthesis. Phenobarbitone administration has no effect on the rate of protein synthesis of ischaemic and post-ischaemic hepatocyte. |
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ISSN: | 0014-4754 1420-9071 |
DOI: | 10.1007/BF01917894 |