Hemodynamic parameters and blood gas analyses in the normal and the cirrhotic rat

Hemodynamic parameters and blood gas analyses in the normal and the cirrhotic rat

Thioacetamide-fed rats developed cirrhosis with portal hypertension (P portal=23.0 +/- 5.2 cm H2O, controls: 14.4 +/- 1.0 cm H2O). The PO2 of liver tissue was markedly reduced in cirrhosis (PO2=7.6 +/- 3.4 torr, controls 22.3 +/- 5.8 torr), and the aortal pH was significantly lower as well. No corre...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Research in experimental medicine 1978-08, Vol.173 (2), p.187-191
Hauptverfasser: Jostarndt, L, Thermann, M, Jerusalem, C R, Zelder, O
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Ascites - etiology
Hypertension, Portal - chemically induced
Liver - metabolism
Liver Cirrhosis - blood
Liver Cirrhosis - chemically induced
Oxygen Consumption
Partial Pressure
Rats
Thioacetamide
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Thioacetamide-fed rats developed cirrhosis with portal hypertension (P portal=23.0 +/- 5.2 cm H2O, controls: 14.4 +/- 1.0 cm H2O). The PO2 of liver tissue was markedly reduced in cirrhosis (PO2=7.6 +/- 3.4 torr, controls 22.3 +/- 5.8 torr), and the aortal pH was significantly lower as well. No correlation was found between portal hypertension, development of large--nodular cirrhosis, and ascites.
ISSN:0300-9130
1433-8580
DOI:10.1007/BF01851876