Antifibrinolytic therapy for prevention of hemorrhage during surgery of the thyroid gland

The amount of fibrinolytic activity in the thyroid gland equals that of the prostate. In order to examine the effect of the antifibrinolytic drug tranexemic acid on perioperative bleeding saline or tranexemic acid were given randomized double blind to 76 consecutive patients who came for scheduled t...

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Veröffentlicht in:	Klinische Wochenschrift 1987-03, Vol.65 (6), p.253-255
Hauptverfasser:	Auvinen, O, Baer, G A, Nordback, I, Saaristo, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenoma - surgery Adult Aged Aged, 80 and over Cyclohexanecarboxylic Acids - therapeutic use Double-Blind Method Fibrinolysis - drug effects Goiter - surgery Hemorrhage - prevention & control Humans Intraoperative Complications - prevention & control Middle Aged Postoperative Complications - prevention & control Random Allocation Thyroid Diseases - surgery Thyroid Neoplasms - surgery Thyroidectomy Tranexamic Acid - therapeutic use
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Beschreibung
Zusammenfassung:	The amount of fibrinolytic activity in the thyroid gland equals that of the prostate. In order to examine the effect of the antifibrinolytic drug tranexemic acid on perioperative bleeding saline or tranexemic acid were given randomized double blind to 76 consecutive patients who came for scheduled thyroid surgery. No significant differences were found in perioperative bleeding between patients in the treatment group (n = 39) and control group (n = 37).
ISSN:	0023-2173 1432-1440
DOI:	10.1007/BF01773442