Murine spermatogonial regeneration after exposure to either X-rays or 15 MeV neutrons

The long-term regeneration of the seminiferous epithelium after irradiation with 15 MeV neutrons was studied in the mouse on a comparative basis; 150 kV X-rays were used as reference-radiation. The mice received total-body exposures at matched doses. The spermatogonial Regeneration Index (RI) was sc...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Radiation and environmental biophysics 1981-01, Vol.19 (1), p.41-49
Hauptverfasser: Langendorff, M, Stevenson, A F
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The long-term regeneration of the seminiferous epithelium after irradiation with 15 MeV neutrons was studied in the mouse on a comparative basis; 150 kV X-rays were used as reference-radiation. The mice received total-body exposures at matched doses. The spermatogonial Regeneration Index (RI) was scored from stained paraffin-sections of testes which were obtained after periodic sacrifice. A biphasic pattern of regeneration was recorded. Dose-independent and dose-dependent effects have been indicated. The radiobiological implications are discussed on a cellular basis.
ISSN:0301-634X
1432-2099
DOI:10.1007/BF01324263