Murine spermatogonial regeneration after exposure to either X-rays or 15 MeV neutrons
The long-term regeneration of the seminiferous epithelium after irradiation with 15 MeV neutrons was studied in the mouse on a comparative basis; 150 kV X-rays were used as reference-radiation. The mice received total-body exposures at matched doses. The spermatogonial Regeneration Index (RI) was sc...
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Veröffentlicht in: | Radiation and environmental biophysics 1981-01, Vol.19 (1), p.41-49 |
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Hauptverfasser: | , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | The long-term regeneration of the seminiferous epithelium after irradiation with 15 MeV neutrons was studied in the mouse on a comparative basis; 150 kV X-rays were used as reference-radiation. The mice received total-body exposures at matched doses. The spermatogonial Regeneration Index (RI) was scored from stained paraffin-sections of testes which were obtained after periodic sacrifice. A biphasic pattern of regeneration was recorded. Dose-independent and dose-dependent effects have been indicated. The radiobiological implications are discussed on a cellular basis. |
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ISSN: | 0301-634X 1432-2099 |
DOI: | 10.1007/BF01324263 |