Blood levels and half-life of methylmethacrylate after tourniquet release during knee arthroplasty

The blood levels and the half-life of monomeric methylmethacrylate after tourniquet release were studied in nine patients with osteoarthrosis or rheumatoid arthritis of the knee joint, treated with the Townley prosthesis under spinal anesthesia. Several ventricular extrasystoles were monitored in on...

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Veröffentlicht in:	Archives of Orthopaedic and Traumatic Surgery 1986, Vol.105 (1), p.36-39
Hauptverfasser:	Svartling, N, Pfäffli, P, Tarkkanen, L
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Bicarbonates - blood Blood Pressure Bone Cements Carbon Dioxide - blood Colloids Female Half-Life Heart Rate Humans Hydrogen-Ion Concentration Knee Prosthesis - adverse effects Knee Prosthesis - methods Male Methylmethacrylate Methylmethacrylates - blood Middle Aged Oxygen - blood Tourniquets
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Zusammenfassung:	The blood levels and the half-life of monomeric methylmethacrylate after tourniquet release were studied in nine patients with osteoarthrosis or rheumatoid arthritis of the knee joint, treated with the Townley prosthesis under spinal anesthesia. Several ventricular extrasystoles were monitored in one patient with high blood levels of monomeric methylmethacrylate (119.80 micrograms/ml). The blood levels of monomeric methylmethacrylate ranged between 0.10 and 1.44 microgram/ml in the rest of the patients. The half-life of monomeric methylmethacrylate in vivo was 47-55 min.
ISSN:	0344-8444 1434-3916
DOI:	10.1007/BF00625658