Filter function of the guinea pig cochlea after degeneration of outer hair cells

After kanamycin induced degeneration of outer hair cells from guinea pigs the tuning properties of primary auditory nerve fibres are compared with those of normal untreated guinea pigs. The existence of fibres with no alteration of the tuning properties leads to the conclusion that there is no neura...

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Veröffentlicht in:	Archives of Oto-Rhino-Laryngology 1977-05, Vol.215 (3-4), p.223-229
Hauptverfasser:	Romahn, G, Boerger, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Auditory Pathways - drug effects Auditory Threshold - drug effects Cochlea - cytology Cochlea - drug effects Guinea Pigs Hair Cells, Auditory - cytology Hair Cells, Auditory - drug effects Kanamycin - adverse effects Mechanoreceptors - drug effects Nerve Degeneration - drug effects Nerve Fibers - drug effects
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Beschreibung
Zusammenfassung:	After kanamycin induced degeneration of outer hair cells from guinea pigs the tuning properties of primary auditory nerve fibres are compared with those of normal untreated guinea pigs. The existence of fibres with no alteration of the tuning properties leads to the conclusion that there is no neural interaction between inner and outer hair cells needed to enhance the frequency selectivity.
ISSN:	0302-9530 1434-4726
DOI:	10.1007/BF00463060