The anemia of childhood revisited

The anemia of childhood revisited

The question of the mechanism of the physiological anemia of childhood was reexamined; we took into consideration the fact that microcytosis is a feature of this anemia as well as the evidence suggesting that the 2,3 DPG/hemoglobin ratio may depend in part on red cell size. In a group of normal, not...

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Veröffentlicht in:Blut 1987-03, Vol.54 (3), p.147-152
Hauptverfasser: TASSIOPOULOS, T, STAMATELOS, G, FILIPPIDOU, E, FILIPPIDIS, F, LAOUTARIS, N, FESSAS, P
Format: Artikel
Sprache:eng
Schlagworte:
2,3-Diphosphoglycerate
Anemia - blood
Anemia - etiology
Anemias. Hemoglobinopathies
Biological and medical sciences
Child
Child, Preschool
Diphosphoglyceric Acids - blood
Diseases of red blood cells
Erythrocyte Indices
Erythrocytes, Abnormal - pathology
Female
Hematologic and hematopoietic diseases
Hemoglobins - analysis
Humans
Male
Medical sciences
Phosphorus - blood
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Zusammenfassung:The question of the mechanism of the physiological anemia of childhood was reexamined; we took into consideration the fact that microcytosis is a feature of this anemia as well as the evidence suggesting that the 2,3 DPG/hemoglobin ratio may depend in part on red cell size. In a group of normal, not-iron deficient children a high inverse correlation was obtained between the MCV and the 2,3 DPG/Hb ratio; this latter ratio did not correlate with serum phosphorus levels, previously incriminated in the indirect causation of the anemia of childhood.
ISSN:0006-5242
1432-0584
DOI:10.1007/BF00320368