Relationship between blood flow and radiostrontium uptake in the healing bone fracture

Relationship between blood flow and radiostrontium uptake in the healing bone fracture

The healing of a diaphyseal tibia fracture was followed in the rat. Callus formation, blood flow and Sr-85 uptake were assessed by a ratio comparison of the fractured to the contralateral side. No correlation was found between blood flow and Sr-85 deposition in the callus and the adjacent bone of th...

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Veröffentlicht in:European Journal of Nuclear Medicine 1979-12, Vol.4 (6), p.413-417
Hauptverfasser: Schümichen, C, Mundriziewski, L, Tischler, E, Hoffmann, G
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Femur - diagnostic imaging
Fractures, Closed - diagnostic imaging
Male
Radionuclide Imaging
Rats
Regional Blood Flow
Strontium Radioisotopes
Tibia - blood supply
Tibial Fractures - diagnostic imaging
Wound Healing
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Zusammenfassung:The healing of a diaphyseal tibia fracture was followed in the rat. Callus formation, blood flow and Sr-85 uptake were assessed by a ratio comparison of the fractured to the contralateral side. No correlation was found between blood flow and Sr-85 deposition in the callus and the adjacent bone of the same extremity. It is concluded that the deposition of a radiopharmaceutical in bone is primarily related to the presence of calcifiable organic bone matrix and only secondarily to the bone formation rate and to variations in the local blood flow.
ISSN:0340-6997
1619-7089
DOI:10.1007/BF00300837