Chemical constituents and cytotoxicity of Lepidotrigona ventralis propolis

Chemical constituents and cytotoxicity of Lepidotrigona ventralis propolis

From propolis of Lepidotrigona ventralis stingless bee collected in Tuyen Quang province, eight compounds were isolated and determined as lantanolic acid (1), moronic acid (2), (+)‐eudesmin (3), (+)‐yangambin (4), (+)‐syringaresinol (5), (+)‐pinoresinol (6), dihydroconiferyl alcohol (7) and vanillin...

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Veröffentlicht in:Vietnam journal of chemistry 2023-02, Vol.61 (1), p.74-79
Hauptverfasser: Thanh, Le Nguyen, Thu, Nguyen Anh, Oanh, Vu Thi Kim, Hue, Vu Thi, Minh, Nguyen Tu, Minh, Nguyen Phan Ngoc, Xuan, Truong Vinh, Phuong, Diep Thi Lan, Lien, Nguyen Thi Phuong
Format: Artikel
Sprache:eng
Schlagworte:
dihydroconyferyl alcohol
lantanolic acid
Lepidotrigona ventralis
lignan
moronic acid
vanillin
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Zusammenfassung:From propolis of Lepidotrigona ventralis stingless bee collected in Tuyen Quang province, eight compounds were isolated and determined as lantanolic acid (1), moronic acid (2), (+)‐eudesmin (3), (+)‐yangambin (4), (+)‐syringaresinol (5), (+)‐pinoresinol (6), dihydroconiferyl alcohol (7) and vanillin (8) using NMR and MS spectral data. Compounds 1 and 2 showed significant cytotoxicity against HepG‐2 cancer cell line with IC50 values of 25.84±0.48 and 39.92±1.14 μg/mL, respectively.
ISSN:0866-7144
2572-8288
2572-8288
DOI:10.1002/vjch.202200031