Cover Picture: Gingival mesenchymal stem cells derived from patients with rheumatoid arthritis treat experimental arthritis (View 6/2024)
In article number 20240021, the authors demonstrate that GMSC derived from patients with Rheumatoid Arthritis shared a similar expression of Immunophenotype with that from health donors. Survived for at least 24 days in a CIA mouse model following injection, RA GMSC reduced the joint histopathologic...
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Veröffentlicht in: | View (Beijing, China) China), 2024-12, Vol.5 (6), p.n/a |
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Hauptverfasser: | , , , , , , , , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | In article number 20240021, the authors demonstrate that GMSC derived from patients with Rheumatoid Arthritis shared a similar expression of Immunophenotype with that from health donors. Survived for at least 24 days in a CIA mouse model following injection, RA GMSC reduced the joint histopathological scores of lymphocytes, osteoclasts, and cartilages. RA‐GMSCs were also effective in suppressing inflamed synoviocyte in a humanized synovitis model as health GMSC does. As a new Elixir from RA patients, autologous GMSCs may have a promising therapeutic potential in patients with RA. |
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ISSN: | 2688-3988 2688-268X |
DOI: | 10.1002/viw2.388 |