Effect of Majoon‐e‐Nisyan (a traditional polyherbal Unani formulation) in animal models of learning and memory

Aim According to classical Unani literature, the multicomponent traditional Unani formulation majoon‐e‐nisyan is used to treat amnesia and cognitive impairment. The purpose of the current study was to evaluate majoon‐e‐nisyan's effectiveness in improving cognitive function. Methods Majoon‐e‐Nisyan was prepared as per traditional method. The cognitive function was evaluated using the passive avoidance test and the water maze experiment in mice. The effectiveness of the test drug was compared to that of the positive control drug, piracetam. Results Passive avoidance data recorded during the memory retention trial showed that transfer latency was significantly increased by majoon‐e‐nisyan at 1000 mg/kg bw (body weight) (p