In vitro inhibitory effects of Sardinian Pistacia lentiscus L. and Pistacia terebinthus L. on metabolic enzymes: Pancreatic lipase, α‐amylase, and α‐glucosidase

Pancreatic triacylglycerol lipase (PL), α‐amylase, and α‐glucosidase are appealing pharmacological targets for the management of dyslipidemia, atherosclerosis, and obesity‐diabetes. Presently, in vitro screening for considerable inhibition of these digestive hydrolases by endemic Sardinian Pistacia...

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Veröffentlicht in:Die Stärke 2015-01, Vol.67 (1-2), p.204-212
Hauptverfasser: Foddai, Marzia, Kasabri, Violet, Afifi, Fatma U, Azara, Emanuela, Petretto, Giacomo L, Pintore, Giorgio
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Sprache:eng
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Zusammenfassung:Pancreatic triacylglycerol lipase (PL), α‐amylase, and α‐glucosidase are appealing pharmacological targets for the management of dyslipidemia, atherosclerosis, and obesity‐diabetes. Presently, in vitro screening for considerable inhibition of these digestive hydrolases by endemic Sardinian Pistacia lentiscus L. and P. terebinthus L. leaves and fruits aqueous extracts (AEs) (Anacardiaceae) was undertaken. The AEs PL‐IC₅₀(µg/mL) in an ascending order were: P. lentiscus leaves; 6.1 ± 0.2
ISSN:0038-9056
1521-379X
DOI:10.1002/star.201400068