Controlled CRISPR‐Cas9 Ribonucleoprotein Delivery for Sensitized Photothermal Therapy (Small 33/2021)

Synergistic Therapy In article number 2101155, Yujun Song, Zhengbao Zha, Xin Han, and co‐workers report a novel thermo‐responsive nanotherapeutic platform, which is triggered by 808 nm near‐infrared light irradiation. This exogenously controlled method can be used in combination tumor therapy, including gene‐therapy, mild‐photothermal therapy, and chemotherapy, which provides a versatile strategy for controlled gene editing and drug release for synergistic therapy with maximizing efficacy and minimizing side‐effects.