Picoanalysis: Picoanalysis of Drugs in Biofluids with Quantitative Label‐Free Surface‐Enhanced Raman Spectroscopy (Small 47/2018)

Picoanalysis: Picoanalysis of Drugs in Biofluids with Quantitative Label‐Free Surface‐Enhanced Raman Spectroscopy (Small 47/2018)

In article number 1802392, Lev T. Perelman and co‐workers report a quantitative label‐free surface‐enhanced Raman spectroscopy (SERS) method for identifying and quantifying drugs at ultralow concentrations. Self‐assembled gold nanoclusters entrap drug molecules and laser light excites the surface pl...

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Veröffentlicht in:Small (Weinheim an der Bergstrasse, Germany) Germany), 2018-11, Vol.14 (47), p.n/a
Hauptverfasser: Turzhitsky, Vladimir, Zhang, Lei, Horowitz, Gary L., Vitkin, Edward, Khan, Umar, Zakharov, Yuri, Qiu, Le, Itzkan, Irving, Perelman, Lev T.
Format: Artikel
Sprache:eng
Schlagworte:
biofluid sensing
drug testing
nanoclusters
optimization
SERS
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Zusammenfassung:In article number 1802392, Lev T. Perelman and co‐workers report a quantitative label‐free surface‐enhanced Raman spectroscopy (SERS) method for identifying and quantifying drugs at ultralow concentrations. Self‐assembled gold nanoclusters entrap drug molecules and laser light excites the surface plasmon resonance, yielding a large SERS signal from the molecule trapped near the hot spot, allowing measurements of drugs in urine samples at clinically relevant concentrations.
ISSN:1613-6810
1613-6829
DOI:10.1002/smll.201870227