Fibronectin-Carbon-Nanotube Hybrid Nanostructures for Controlled Cell Growth

Fibronectin–carbon‐nanotube (CNT) hybrid nanostructures are proposed as a platform to control the adhesion and growth of cells. The structure and role of extracellular matrix proteins, such as fibronectin, in the CNT–cell interactions are revealed by atomic force microscopy. The focal adhesion sites...

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Veröffentlicht in:	Small (Weinheim an der Bergstrasse, Germany) Germany), 2011-01, Vol.7 (1), p.56-61
Hauptverfasser:	Namgung, Seon, Kim, Taekyeong, Baik, Ku Youn, Lee, Minbaek, Nam, Jwa-Min, Hong, Seunghun
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals atomic force microscopy Extracellular Matrix Proteins - chemistry Extracellular Matrix Proteins - pharmacology fibronectin-carbon-nanotube hybrids Fibronectins - chemistry Fibronectins - pharmacology Fluorescent Antibody Technique HeLa Cells Humans Mesenchymal Stromal Cells - cytology Mesenchymal Stromal Cells - drug effects Mice Microscopy, Atomic Force Nanostructures - chemistry Nanotubes, Carbon - chemistry NIH 3T3 Cells selective cell adhesion selective cell growth
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Beschreibung
Zusammenfassung:	Fibronectin–carbon‐nanotube (CNT) hybrid nanostructures are proposed as a platform to control the adhesion and growth of cells. The structure and role of extracellular matrix proteins, such as fibronectin, in the CNT–cell interactions are revealed by atomic force microscopy. The focal adhesion sites on fibronectin–carbon‐nanotube hybrid nanostructures induce selective cell growth, including selective filopodial growth of human mesenchymal stem cells.
ISSN:	1613-6810 1613-6829
DOI:	10.1002/smll.201001513