Synthesis, Characterization and Biological Properties of Mn (II) and Cu (II) Complexes with Sulfonamide and Imidazole Derivatives: Genotoxicity, ADME Profile, and Molecular Docking Studies

The synthesis, characterization, and comparative biological properties of manganese (II) and copper (II) complexes formed with two heterocyclic ligands used in the pharmaceutical field are reported. The characterization of the metal complexes involved elemental analysis, FAB mass spectroscopy, ESR,...

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Veröffentlicht in:ChemistrySelect (Weinheim) 2023-10, Vol.8 (40)
Hauptverfasser: Bouchoucha, Afaf, Amine Bourouai, Mohamed, Si Larbi, Karima, Merazka, Hadjer, Boulanouar, Salah, Djabbar, Safia
Format: Artikel
Sprache:eng
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Zusammenfassung:The synthesis, characterization, and comparative biological properties of manganese (II) and copper (II) complexes formed with two heterocyclic ligands used in the pharmaceutical field are reported. The characterization of the metal complexes involved elemental analysis, FAB mass spectroscopy, ESR, FTIR, UV‐Visible spectroscopy, and conductometry. The spectroscopic data allowed the determination of the coordination mode and the geometry of all the coordination compounds.
ISSN:2365-6549
2365-6549
DOI:10.1002/slct.202302779