Rubiadin Regulates Bone Metabolism in Ovariectomized Rat Model by Inhibition of osteoclast formation and differentiation

Rubiadin Regulates Bone Metabolism in Ovariectomized Rat Model by Inhibition of osteoclast formation and differentiation

The present study investigated the effect of rubiadin from morinda officinalis on bone metabolism in an ovariectomized rat model. Results from the MTT test showed that the best drug concentration was 0.6 mg for 24 h (P>0.05). Compared with the Control group, the femoral bone mineral density in th...

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Veröffentlicht in:ChemistrySelect (Weinheim) 2023-03, Vol.8 (11), p.n/a
Hauptverfasser: Huang, Hui, Chen, Jian, Lin, Zhengkun, Lin, Xiaomei
Format: Artikel
Sprache:eng
Schlagworte:
Bone Mineral Density
High throughput sequencing
Osteoclast
Osteoporosis
Rubiadin
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Zusammenfassung:The present study investigated the effect of rubiadin from morinda officinalis on bone metabolism in an ovariectomized rat model. Results from the MTT test showed that the best drug concentration was 0.6 mg for 24 h (P>0.05). Compared with the Control group, the femoral bone mineral density in the experimental group treated with rubiadin was significantly higher (P
ISSN:2365-6549
2365-6549
DOI:10.1002/slct.202300115