Application of New Magnetic Graphene Oxide‐Porphyrin Nanoparticles for Synthesis of Pyridines and Pyrimidines via Anomeric‐Based Oxidation

Herein joining of poly graphene oxide‐porphyrin to magnetic nanoparticles {poly Fe3O4@SiO2@(CH2)3‐GO‐[PTTA‐NH−Ni] MNPs} was occurred. The synthesized catalyst was characterized by several techniques such as FT‐IR, CHN elemental analysis, EDX, WDX elemental maps, TGA, DTG, DTA, XRD, FE‐SEM, TEM, BET, BJH, VSM, and ICP‐AES. The described magnetic nanoparticles were employed as a benign catalyst for the expedient synthesis of 5‐amino‐7‐aryl‐2‐oxo‐2,3‐dihydrothiazolo[4,5‐b] pyridine‐6‐carbonitriles via anomeric‐based oxidation mechanistic pathway. Target molecules were prepared through a four‐component reaction of 2,4‐thiazolidinedione, aldehydes, malononitrile, and ammonium acetate under solvent‐free conditions at 75 °C. Also, the application of the presented catalyst was investigated under the same reaction conditions for the synthesis of 5,7‐diaryl‐4,7‐dihydro‐[1,2,4]triazolo[1,5‐a]pyrimidines through the three‐component reaction of aldehydes, acetophenones, and 3‐amino‐1,2,4‐triazole. Poly Fe3O4@SiO2@(CH2)3‐GO‐[PTTA‐NH‐Ni] MNPs was used as a benign catalyst for the synthesis of several heterocyclic compounds such as pyridines and pyrimidines via anomeric‐based oxidation mechanistic pathway. This simple technique has the advantages of being environmentally benign, appropriate yield, short reaction time, and ease of the process.