Synthesis, Characterization, Antimicrobial and Corrosion Inhibition Studies of Fused Oxadiazolo‐quinolines

A novel series of 2‐(4‐substituted phenyl)‐6/8‐substituted‐ [1,3,4] oxadiazolo[2′,3′:2,3][1,3]thiazino[6,5‐b]quinolin‐11(3aH)‐ones were synthesized. Their structures have been characterized using standard spectroscopic techniques such as Infrared, Nuclear Magnetic Resonance, and Mass Spectroscopy. All the newly synthesized compounds were screened for their antibacterial and antifungal activities by the cup plate diffusion method. Antimicrobial studies revealed that compounds showed good to significant activity against tested strains. One of the compounds was evaluated for corrosion inhibition studies by potentiodynamic polarization and electrochemical impedance method in 0.1 M hydrochloric acid solution for mild steel. The tested compound had exhibited a good inhibitory action against corrosion of mild steel in the medium investigated. A novel series of 2‐(4‐substituted phenyl)‐6/8‐substituted‐[1,3,4]oxadiazolo[2′,3′:2,3][1,3]thiazino[6,5‐b]quinolin‐11(3aH)‐ones were synthesized, and characterized by standard spectroscopic techniques such as IR, NMR and Mass Spectroscopy. One of the tested compounds had exhibited a good inhibitory action against corrosion of mild steel in the medium investigated. Antimicrobial studies revealed that the compounds showed good to significant activity against tested strains.