Design, Network Analysis, In Silico Modeling and Synthesis of Benzimidazoles Nanocomposites as Anticancer Agent

A novel benzimidazole was synthesized and formulated as a nanocomposite and it was characterized by spectral, elemental analyses followed by the nanocomposite was screened for their anticancer activity. The anticancer screening of synthesized compounds was evaluated against two different cancer cell lines. Molecular modelling was performed to identify drug‐receptor interaction using three dimensional crystal structures of human protein p38α. The formulated nanocomposite produces p38α MAP Kinases inhibitory activity with IC50