Regioselective Synthesis of Pyrrolylpyrazole as a Multifunctional Compound: Potential Antibacterial as well as Anticancer Agent

A regioselective synthesis of 3‐pyrazolyl‐4‐aryl substituted pyrrole derivatives from α‐aroylidineketene dithioacetals using a convenient and efficient protocol. The pyrrolylpyrazole molecules were expected to have good application in biological system consequently most of the compounds shows excellent antibacterial activity when compared with streptomycin drug. All the synthesized compounds were studied for their anticancer activity in which 5 b, 5 e, 5 g, 5 i have cytotoxic potential on cervical cancer cells at lower concentration. A regioselective synthesis of 3‐pyrazolyl‐4‐aryl substituted pyrrole derivatives from α‐aroylidineketene dithioacetals using a convenient and efficient protocol. All the compounds 5a‐j show good antibacterial activity and among them 5b, 5e, 5 g & 5i could effectively control cervical cancer even at lower concentration.