On-line isotachophoretic analyte focusing for improvement of detection limits in capillary electrophoresis/electrospray mass spectrometry

Detectability enhancement in capillary electrophoresis/mass spectrometry (CE/MS) has been realized using on‐line isotachophoretic (ITP) analyte focusing. This is demonstrated for the analysis of a mixture of anthracyclines, showing on at least 200‐fold improvement detectable concentration for ITP/CE...

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Veröffentlicht in:	Rapid communications in mass spectrometry 1992-09, Vol.6 (9), p.560-563
Hauptverfasser:	Tinke, A. P., Reinhoud, N. J., Niessen, W. M. A., Tjaden, U. R., van der Greef, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Aromatic and heterocyclic compounds Biological and medical sciences Fundamental and applied biological sciences. Psychology Heterocyclic compounds, pigments Other biological molecules
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Detectability enhancement in capillary electrophoresis/mass spectrometry (CE/MS) has been realized using on‐line isotachophoretic (ITP) analyte focusing. This is demonstrated for the analysis of a mixture of anthracyclines, showing on at least 200‐fold improvement detectable concentration for ITP/CE/MS compared to CE/MS using an electrospray (ESP) interface.
ISSN:	0951-4198 1097-0231
DOI:	10.1002/rcm.1290060905