Production of Small Libraries Optimising and Examining the Scope of Aqueous Acceleration of the Passerini Reaction
It has been reported that the rate of the Passerini reaction is accelerated in water or in a mixture of water and an organic solvent. Here, the synthesis of small libraries using the Passerini reaction in a biphasic system is described. Examination of the effects of stoichiometry and different reage...
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| Veröffentlicht in: | QSAR & combinatorial science 2006-06, Vol.25 (5-6), p.484-490 |
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| container_issue | 5-6 |
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| container_title | QSAR & combinatorial science |
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| creator | Extance, Andrew R. Benzies, David W. M. Morrish, James J. |
| description | It has been reported that the rate of the Passerini reaction is accelerated in water or in a mixture of water and an organic solvent. Here, the synthesis of small libraries using the Passerini reaction in a biphasic system is described. Examination of the effects of stoichiometry and different reagents demonstrated the ability to produce material of high purity without chromatography, within a specified structural scope. |
| doi_str_mv | 10.1002/qsar.200540197 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 1611-020X |
| ispartof | QSAR & combinatorial science, 2006-06, Vol.25 (5-6), p.484-490 |
| issn | 1611-020X 1611-0218 |
| language | eng |
| recordid | cdi_crossref_primary_10_1002_qsar_200540197 |
| source | Wiley Online Library Journals |
| subjects | Aqueous solvent systems High-throughput chemistry Library Synthesis Multicomponent chemistry Passerini reaction |
| title | Production of Small Libraries Optimising and Examining the Scope of Aqueous Acceleration of the Passerini Reaction |
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