Plumieride from Allamanda cathartica as an antidermatophytic agent

Plumieride has been isolated as an active principle of the leaves of Allamanda cathartica. It showed strong fungitoxicity against some dermatophytes causing dermatomycosis to animals and human beings. It exhibited a noncytotoxic nature against a P388 mouse leukaemia cell line. Copyright © 2002 John...

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Veröffentlicht in:	Phytotherapy research 2002-06, Vol.16 (4), p.393-394
Hauptverfasser:	Tiwari, T. N., Pandey, V. B., Dubey, N. K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Allamanda cathartica Animals Antifungal Agents - chemistry Antifungal Agents - isolation & purification Antifungal Agents - pharmacology Apocynaceae - chemistry Biological and medical sciences Cell Division - drug effects cytotoxicity Dermatomycoses - pathology Epidermophyton - drug effects fungitoxicity Furans - chemistry Furans - isolation & purification Furans - pharmacology General pharmacology Humans Inhibitory Concentration 50 Leukemia P388 - pathology Medical sciences Mice Microsporum - drug effects Molecular Structure Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant Extracts - chemistry Plant Leaves - chemistry plumieride Spiro Compounds - chemistry Spiro Compounds - isolation & purification Spiro Compounds - pharmacology Tumor Cells, Cultured
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Zusammenfassung:	Plumieride has been isolated as an active principle of the leaves of Allamanda cathartica. It showed strong fungitoxicity against some dermatophytes causing dermatomycosis to animals and human beings. It exhibited a noncytotoxic nature against a P388 mouse leukaemia cell line. Copyright © 2002 John Wiley & Sons, Ltd.
ISSN:	0951-418X 1099-1573
DOI:	10.1002/ptr.967