Cytostatic activity of Achillea ageratum L

The cytostatic activity of a chloroform extract and two isolated compounds from Achillea ageratum L. (Asteraceae) was determined in vitro against Hep‐2 and McCoy cells. The chloroform extract exhibited a high degree of growth inhibition compared with the values obtained with the 6‐mercaptopurine (po...

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Veröffentlicht in:	Phytotherapy research 2001-11, Vol.15 (7), p.633-634
Hauptverfasser:	GOMEZ, M. A, GARCIA, M. D, SAENZ, M. T
Format:	Artikel
Sprache:	eng
Schlagworte:	Achillea ageratum antimitotic activity Antineoplastic Agents - toxicity Asteraceae Biological and medical sciences cytostatic activity General pharmacology Hep-2 cells Humans Inhibitory Concentration 50 McCoy cells Medical sciences Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Phytotherapy Plant Extracts - toxicity Sitosterols - toxicity stigmasterol Stigmasterol - toxicity Tumor Cells, Cultured - drug effects β-sitosterol
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Zusammenfassung:	The cytostatic activity of a chloroform extract and two isolated compounds from Achillea ageratum L. (Asteraceae) was determined in vitro against Hep‐2 and McCoy cells. The chloroform extract exhibited a high degree of growth inhibition compared with the values obtained with the 6‐mercaptopurine (positive control) against both cultures. Stigmasterol and β‐sitosterol, isolated from the chloroform extract, showed a high degree of growth inhibition. Copyright © 2001 John Wiley & Sons, Ltd.
ISSN:	0951-418X 1099-1573
DOI:	10.1002/ptr.837