Biodegradable stereocomplex materials of polylactide-grafted dextran exhibiting soft and tough properties in dry and wet states

Water‐swellable biodegradable materials exhibiting mechanically tenacious and tough characters in the wet state were prepared by a simple blend of two enantiomeric polylactide‐grafted dextran copolymers (Dex‐g‐PLLA and Dex‐g‐PDLA). DSC and WAXD analyses demonstrated the formation of SC crystals in the copolymer blend films. SC blend films showed lamellar‐type microphase‐separated structures. When swollen with water, these blend films showed the same level of tensile strengths and Young's modulus as the films in the dry state. SC blend films degraded gradually over a month under physiological conditions with a degradation rate faster than the corresponding Dex‐g‐PLLA films. The SC‐forming enantiomeric mixture of polylactide‐grafted polysaccharides should be a good candidate for an implantable biocompatible material exhibiting favorable mechanical properties and degradation behavior. © 2012 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2012 Water‐swellable biodegradable materials exhibiting mechanically tenacious and tough characters in the wet state were prepared by a simple blend of two enantiomeric polylactide‐grafted dextran copolymers (Dex‐g‐PLLA and Dex‐g‐PDLA). Interestingly, the swelled blend films showed the same level of tensile strengths and Young's modulus as the films in the dry state. The differences in thermal and degradation properties and the microphase‐separated structures of the blend films with the corresponding Dex‐g‐PLLA films are also discussed.