Front Cover: Organellar Omics – A Reviving Strategy to Untangle the Biomolecular Complexity of the Cell

DOI: 10.1002/pmic.201700113 The cover art represents the experimental workflow to analyse the biomolecular composition of purified plasma membranes and lysosomes. The methodology is based on the use of superparamagnetic iron oxide nanoparticles (SPIONs) with different functionalized groups. Aminolipid‐coated SPIONs are targeted to the cell surface while DMSA‐coated SPIONs are taken up by cells and chased to lysosomes. Magnetically isolated compartments are compatible for subsequent proteome and lipidome analysis. In their review, article number 1700113, Tharkeshwar, Gevaert and Annaert go more deep into the different available strategies for subcellular omics analysis.