Application of a secondary ion mass spectrometer as a detector in liquid chromatography

Recently developed new techniques of ion formation from organic solids may become very useful in the application of mass spectrometers as detector units in liquid chromatography. Details of a liquid chromatograph mass spectrometer coupling device are presented. Some features of this device, combined...

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Veröffentlicht in:Organic Mass Spectrometry 1980-09, Vol.15 (9), p.459-462
Hauptverfasser: Benninghoven, A., Eicke, A., Junack, M., Sichtermann, W., Krizek, J., Peters, H.
Format: Artikel
Sprache:eng
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Zusammenfassung:Recently developed new techniques of ion formation from organic solids may become very useful in the application of mass spectrometers as detector units in liquid chromatography. Details of a liquid chromatograph mass spectrometer coupling device are presented. Some features of this device, combined with a quadrupole secondary ion mass spectrometer, are demonstrated experimentally by the analysis of aqueous solutions of leucine and cytosine. It is demonstrated that the sensitivity of the liquid chromatography secondary ion mass spectrometry combination covers the concentration range occurring in liquid chromatography.
ISSN:0030-493X
1096-9888
DOI:10.1002/oms.1210150907