In vitro characterization of an Fe 8 cluster as potential MRI contrast agent
The complex [(tacn) 6 Fe 8 (µ 3 ‐O) 2 (µ 2 ‐OH) 12 ]Br 8 ·9H 2 O (Fe 8 ) was evaluated in vitro as a new kind of possible MRI contrast agent. Relaxivities were measured at 1.41 and 9.4 T for Fe 8 and commercial Gd‐DTPA dissolved in PBS. There was significant difference for r 1 and r 2 values between...
Gespeichert in:
| Veröffentlicht in: | NMR in biomedicine 2005-08, Vol.18 (5), p.300-307 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Zusammenfassung: | The complex [(tacn)
6
Fe
8
(µ
3
‐O)
2
(µ
2
‐OH)
12
]Br
8
·9H
2
O (Fe
8
) was evaluated
in vitro
as a new kind of possible MRI contrast agent. Relaxivities were measured at 1.41 and 9.4 T for Fe
8
and commercial Gd‐DTPA dissolved in PBS. There was significant difference for
r
1
and
r
2
values between Fe
8
and Gd‐DTPA at high field (9.4 T) and for
r
1
at low field (1.4 T) (
p |
|---|---|
| ISSN: | 0952-3480 1099-1492 |
| DOI: | 10.1002/nbm.959 |