Distant effects of locally injected botulinum toxin: A double-blind study of single fiber EMG changes

We used single fiber electromyography (SFEMG) to study 42 patients who had enroleld in a double‐blind, placebo‐controlled trial undertaken to assess the efficacy of botulinum toxin (BTX) injection of neck muscles to treat torticollis. SFEMG in a limb muscle was performed before treatment, 2, and 12...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Muscle & nerve 1991-07, Vol.14 (7), p.672-675
Hauptverfasser:	Lange, Dale J., Rubin, Michael, Greene, Paul E., Kang, Un J., Moskowitz, Carol B., Brin, Mitchell F., Lovelace, Robert E., Fahn, Stanley
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Botulinum Toxins - therapeutic use botulium toxin Double-Blind Method Electromyography Female Humans Injections, Intramuscular jitter Male Medical sciences Miscellaneous Muscle Contraction - drug effects Muscles - drug effects Muscles - physiology Neck Muscles Neuropharmacology Pharmacology. Drug treatments remote effects single fiber EMG Time Factors torticollis Torticollis - therapy
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	We used single fiber electromyography (SFEMG) to study 42 patients who had enroleld in a double‐blind, placebo‐controlled trial undertaken to assess the efficacy of botulinum toxin (BTX) injection of neck muscles to treat torticollis. SFEMG in a limb muscle was performed before treatment, 2, and 12 weeks after injection of placebo or BTX. Before treatment, the mean jitter was 26.8 μsec in patients who were to receive BTX, and 25.7 μsec in the placebo group. Two weeks after injection, mean jitter in the group receiving BTX was 43.6 μsec. In the placebo group, it was 26.5 μsec (P =
ISSN:	0148-639X 1097-4598
DOI:	10.1002/mus.880140711