Simultaneous Optimization of MP2RAGE T 1 -weighted (UNI) and FLuid And White matter Suppression (FLAWS) brain images at 7T using Extended Phase Graph (EPG) Simulations

Simultaneous Optimization of MP2RAGE T 1 -weighted (UNI) and FLuid And White matter Suppression (FLAWS) brain images at 7T using Extended Phase Graph (EPG) Simulations

The MP2RAGE sequence is typically optimized for either T -weighted uniform image (UNI) or gray matter-dominant fluid and white matter suppression (FLAWS) contrast images. Here, the purpose was to optimize an MP2RAGE protocol at 7 Tesla to provide UNI and FLAWS images simultaneously in a clinically a...

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Veröffentlicht in:Magnetic resonance in medicine 2023-03, Vol.89 (3), p.937-950
Hauptverfasser: Dokumacı, Ayşe Sıla, Aitken, Fraser R, Sedlacik, Jan, Bridgen, Pip, Tomi-Tricot, Raphael, Mooiweer, Ronald, Vecchiato, Katy, Wilkinson, Tom, Casella, Chiara, Giles, Sharon, Hajnal, Joseph V, Malik, Shaihan J, O'Muircheartaigh, Jonathan, Carmichael, David W
Format: Artikel
Sprache:eng
Schlagworte:
Brain - diagnostic imaging
Child
Gray Matter
Humans
Magnetic Resonance Imaging - methods
Neuroimaging
White Matter - diagnostic imaging
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Zusammenfassung:The MP2RAGE sequence is typically optimized for either T -weighted uniform image (UNI) or gray matter-dominant fluid and white matter suppression (FLAWS) contrast images. Here, the purpose was to optimize an MP2RAGE protocol at 7 Tesla to provide UNI and FLAWS images simultaneously in a clinically applicable acquisition time at 85% of the optimal UNI contrast-to-noise ratio. Using TI /TI /TR of 650/2280/4000 ms, 6/8 partial Fourier in the inner phase-encoding direction, and GRAPPA factor = 4 in the other, images with 0.65 mm isotropic resolution were produced in
ISSN:0740-3194
1522-2594
DOI:10.1002/mrm.29479