1 H and 13 C NMR spectral assignment of N , N ′‐disubstituted thiourea and urea derivatives active against nitric oxide synthase
The 1 H and 13 C NMR resonances of seventeen N ‐alkyl and aryl‐ N ′‐[3‐hydroxy‐3‐(2‐nitro‐5‐substitutedphenyl)propyl]‐thioureas and ureas ( 1–17 ), and seventeen N ‐alkyl or aryl‐ N ′‐[3‐(2‐amino‐5‐substitutedphenyl)‐3‐hydroxypropyl]‐thioureas and ureas ( 18–34 ), designed as NOS inhibitors, were as...
Gespeichert in:
| Veröffentlicht in: | Magnetic resonance in chemistry 2016-10, Vol.54 (10), p.793-799 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 799 |
|---|---|
| container_issue | 10 |
| container_start_page | 793 |
| container_title | Magnetic resonance in chemistry |
| container_volume | 54 |
| creator | Chayah, Mariem Camacho, M. Encarnación Carrión, M. Dora Gallo, Miguel A. |
| description | The
1
H and
13
C NMR resonances of seventeen
N
‐alkyl and aryl‐
N
′‐[3‐hydroxy‐3‐(2‐nitro‐5‐substitutedphenyl)propyl]‐thioureas and ureas (
1–17
), and seventeen
N
‐alkyl or aryl‐
N
′‐[3‐(2‐amino‐5‐substitutedphenyl)‐3‐hydroxypropyl]‐thioureas and ureas (
18–34
), designed as NOS inhibitors, were assigned completely using the concerted application of one‐ and two‐dimensional experiments (DEPT, HSQC and HMBC). NOESY studies confirm the preferred conformation of these compounds. Copyright © 2016 John Wiley & Sons, Ltd. |
| doi_str_mv | 10.1002/mrc.4455 |
| format | Article |
| fullrecord | <record><control><sourceid>crossref</sourceid><recordid>TN_cdi_crossref_primary_10_1002_mrc_4455</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>10_1002_mrc_4455</sourcerecordid><originalsourceid>FETCH-LOGICAL-c725-29c95fff493ceafdc4f0ef828658b439782ca9859375c03417f691f8aa654cec3</originalsourceid><addsrcrecordid>eNotkEFOAjEYRhujiYgmHuFfunCwnbYz7dIQFRPExLBwN_nptFADM6QtRHYsPIBn8UicREAXX963eotHyDWjPUZpfrcIpieElCekw6guMyHV-ynp0FLojEnFzslFjB-UUq1L3iFfDAaATQ2MQx9GL28Ql9akgHPAGP20WdgmQetgBLf77bY_u-137eNqEpNPq2RrSDPfroLFo-Z4ahv8GpNf2whoDgScom9igsan4A20n762EDdNmmG0l-TM4Tzaq392yfjxYdwfZMPXp-f-_TAzZS6zXBstnXNCc2PR1UY4ap3KVSHVRHBdqtygVlLzUhrKBStdoZlTiIUUxhreJTd_WhPaGIN11TL4BYZNxWh1iFft41WHePwXpNJk-A</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>1 H and 13 C NMR spectral assignment of N , N ′‐disubstituted thiourea and urea derivatives active against nitric oxide synthase</title><source>Wiley Online Library Journals Frontfile Complete</source><creator>Chayah, Mariem ; Camacho, M. Encarnación ; Carrión, M. Dora ; Gallo, Miguel A.</creator><creatorcontrib>Chayah, Mariem ; Camacho, M. Encarnación ; Carrión, M. Dora ; Gallo, Miguel A.</creatorcontrib><description>The
1
H and
13
C NMR resonances of seventeen
N
‐alkyl and aryl‐
N
′‐[3‐hydroxy‐3‐(2‐nitro‐5‐substitutedphenyl)propyl]‐thioureas and ureas (
1–17
), and seventeen
N
‐alkyl or aryl‐
N
′‐[3‐(2‐amino‐5‐substitutedphenyl)‐3‐hydroxypropyl]‐thioureas and ureas (
18–34
), designed as NOS inhibitors, were assigned completely using the concerted application of one‐ and two‐dimensional experiments (DEPT, HSQC and HMBC). NOESY studies confirm the preferred conformation of these compounds. Copyright © 2016 John Wiley & Sons, Ltd.</description><identifier>ISSN: 0749-1581</identifier><identifier>EISSN: 1097-458X</identifier><identifier>DOI: 10.1002/mrc.4455</identifier><language>eng</language><ispartof>Magnetic resonance in chemistry, 2016-10, Vol.54 (10), p.793-799</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c725-29c95fff493ceafdc4f0ef828658b439782ca9859375c03417f691f8aa654cec3</citedby><cites>FETCH-LOGICAL-c725-29c95fff493ceafdc4f0ef828658b439782ca9859375c03417f691f8aa654cec3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids></links><search><creatorcontrib>Chayah, Mariem</creatorcontrib><creatorcontrib>Camacho, M. Encarnación</creatorcontrib><creatorcontrib>Carrión, M. Dora</creatorcontrib><creatorcontrib>Gallo, Miguel A.</creatorcontrib><title>1 H and 13 C NMR spectral assignment of N , N ′‐disubstituted thiourea and urea derivatives active against nitric oxide synthase</title><title>Magnetic resonance in chemistry</title><description>The
1
H and
13
C NMR resonances of seventeen
N
‐alkyl and aryl‐
N
′‐[3‐hydroxy‐3‐(2‐nitro‐5‐substitutedphenyl)propyl]‐thioureas and ureas (
1–17
), and seventeen
N
‐alkyl or aryl‐
N
′‐[3‐(2‐amino‐5‐substitutedphenyl)‐3‐hydroxypropyl]‐thioureas and ureas (
18–34
), designed as NOS inhibitors, were assigned completely using the concerted application of one‐ and two‐dimensional experiments (DEPT, HSQC and HMBC). NOESY studies confirm the preferred conformation of these compounds. Copyright © 2016 John Wiley & Sons, Ltd.</description><issn>0749-1581</issn><issn>1097-458X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><recordid>eNotkEFOAjEYRhujiYgmHuFfunCwnbYz7dIQFRPExLBwN_nptFADM6QtRHYsPIBn8UicREAXX963eotHyDWjPUZpfrcIpieElCekw6guMyHV-ynp0FLojEnFzslFjB-UUq1L3iFfDAaATQ2MQx9GL28Ql9akgHPAGP20WdgmQetgBLf77bY_u-137eNqEpNPq2RrSDPfroLFo-Z4ahv8GpNf2whoDgScom9igsan4A20n762EDdNmmG0l-TM4Tzaq392yfjxYdwfZMPXp-f-_TAzZS6zXBstnXNCc2PR1UY4ap3KVSHVRHBdqtygVlLzUhrKBStdoZlTiIUUxhreJTd_WhPaGIN11TL4BYZNxWh1iFft41WHePwXpNJk-A</recordid><startdate>201610</startdate><enddate>201610</enddate><creator>Chayah, Mariem</creator><creator>Camacho, M. Encarnación</creator><creator>Carrión, M. Dora</creator><creator>Gallo, Miguel A.</creator><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>201610</creationdate><title>1 H and 13 C NMR spectral assignment of N , N ′‐disubstituted thiourea and urea derivatives active against nitric oxide synthase</title><author>Chayah, Mariem ; Camacho, M. Encarnación ; Carrión, M. Dora ; Gallo, Miguel A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c725-29c95fff493ceafdc4f0ef828658b439782ca9859375c03417f691f8aa654cec3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chayah, Mariem</creatorcontrib><creatorcontrib>Camacho, M. Encarnación</creatorcontrib><creatorcontrib>Carrión, M. Dora</creatorcontrib><creatorcontrib>Gallo, Miguel A.</creatorcontrib><collection>CrossRef</collection><jtitle>Magnetic resonance in chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chayah, Mariem</au><au>Camacho, M. Encarnación</au><au>Carrión, M. Dora</au><au>Gallo, Miguel A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>1 H and 13 C NMR spectral assignment of N , N ′‐disubstituted thiourea and urea derivatives active against nitric oxide synthase</atitle><jtitle>Magnetic resonance in chemistry</jtitle><date>2016-10</date><risdate>2016</risdate><volume>54</volume><issue>10</issue><spage>793</spage><epage>799</epage><pages>793-799</pages><issn>0749-1581</issn><eissn>1097-458X</eissn><abstract>The
1
H and
13
C NMR resonances of seventeen
N
‐alkyl and aryl‐
N
′‐[3‐hydroxy‐3‐(2‐nitro‐5‐substitutedphenyl)propyl]‐thioureas and ureas (
1–17
), and seventeen
N
‐alkyl or aryl‐
N
′‐[3‐(2‐amino‐5‐substitutedphenyl)‐3‐hydroxypropyl]‐thioureas and ureas (
18–34
), designed as NOS inhibitors, were assigned completely using the concerted application of one‐ and two‐dimensional experiments (DEPT, HSQC and HMBC). NOESY studies confirm the preferred conformation of these compounds. Copyright © 2016 John Wiley & Sons, Ltd.</abstract><doi>10.1002/mrc.4455</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0749-1581 |
| ispartof | Magnetic resonance in chemistry, 2016-10, Vol.54 (10), p.793-799 |
| issn | 0749-1581 1097-458X |
| language | eng |
| recordid | cdi_crossref_primary_10_1002_mrc_4455 |
| source | Wiley Online Library Journals Frontfile Complete |
| title | 1 H and 13 C NMR spectral assignment of N , N ′‐disubstituted thiourea and urea derivatives active against nitric oxide synthase |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-27T23%3A21%3A15IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-crossref&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=1%20H%20and%2013%20C%20NMR%20spectral%20assignment%20of%20N%20,%20N%20%E2%80%B2%E2%80%90disubstituted%20thiourea%20and%20urea%20derivatives%20active%20against%20nitric%20oxide%20synthase&rft.jtitle=Magnetic%20resonance%20in%20chemistry&rft.au=Chayah,%20Mariem&rft.date=2016-10&rft.volume=54&rft.issue=10&rft.spage=793&rft.epage=799&rft.pages=793-799&rft.issn=0749-1581&rft.eissn=1097-458X&rft_id=info:doi/10.1002/mrc.4455&rft_dat=%3Ccrossref%3E10_1002_mrc_4455%3C/crossref%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |