NMR diffusion coefficient study of steroid-cyclodextrin inclusion complexes

NMR diffusion coefficient study of steroid-cyclodextrin inclusion complexes

The complexes formed by the steroid rocuronium bromide with four different cyclodextrins (β‐cyclodextrin, γ‐cyclodextrin, Org 26054 and Org 25969) were investigated. The diffusion coefficients of the steroid–cyclodextrin complexes were 6–15% lower than those of the native cyclodextrins, consistent w...

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Veröffentlicht in:Magnetic resonance in chemistry 2002-12, Vol.40 (13), p.S106-S109
Hauptverfasser: Cameron, Kenneth S., Fielding, Lee
Format: Artikel
Sprache:eng
Schlagworte:
cyclodextrins
diffusion
inclusion complexes
NMR
steroids
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Zusammenfassung:The complexes formed by the steroid rocuronium bromide with four different cyclodextrins (β‐cyclodextrin, γ‐cyclodextrin, Org 26054 and Org 25969) were investigated. The diffusion coefficients of the steroid–cyclodextrin complexes were 6–15% lower than those of the native cyclodextrins, consistent with a 1 : 1 stoichiometry for all of the complexes. Copyright © 2002 John Wiley & Sons, Ltd.
ISSN:0749-1581
1097-458X
DOI:10.1002/mrc.1083