Reversal of radiation-induced neutropenia by granulocyte colony-stimulating factor

Reversal of radiation-induced neutropenia by granulocyte colony-stimulating factor

Myelosuppression is a common sequelae of radiotherapy, occasionally delaying the completion of treatment. In this report, we describe successful reversal of radiation‐induced neutropenia in a child receiving craniospinal irradiation by granulocyte colonystimulating factor (G‐CSF). We suggest that G‐...

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Veröffentlicht in:Medical and pediatric oncology 1992, Vol.20 (3), p.240-242
Hauptverfasser: Marks, Lawrence B., Friedman, Henry S., Kurtzberg, Joanne, Oakes, W. Jerry, Hockenberger, Beverly M.
Format: Artikel
Sprache:eng
Schlagworte:
Cerebellar Neoplasms - radiotherapy
granulocyte colony-stimulating factor
Granulocyte Colony-Stimulating Factor - therapeutic use
Humans
Infant
Male
Medulloblastoma - radiotherapy
neutropenia
Neutropenia - drug therapy
Neutropenia - etiology
radiotherapy
Radiotherapy - adverse effects
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Zusammenfassung:Myelosuppression is a common sequelae of radiotherapy, occasionally delaying the completion of treatment. In this report, we describe successful reversal of radiation‐induced neutropenia in a child receiving craniospinal irradiation by granulocyte colonystimulating factor (G‐CSF). We suggest that G‐CSF be considered as supportive care in patients in whom neutropenia develops during radiotherapy. © 1992 Wiley‐Liss, Inc.
ISSN:0098-1532
1096-911X
DOI:10.1002/mpo.2950200312