Back Cover: Aromatic‐Turmerone Attenuates LPS‐Induced Neuroinflammation and Consequent Memory Impairment by Targeting TLR4‐Dependent Signaling Pathway

Mol. Nutr. Food Res. 2018, 62, 1700281 DOI: 10.1002/mnfr.201700281 Oral administration of aromatic‐turmerone could reverse lipopolysaccharide (LPS)‐induced memory disturbance and normalize glucose intake and metabolism in the brains of mice. Moreover, aromatic‐turmerone significantly limits brain damage by inhibiting the activation of microglia and the generation of inflammatory cytokines. Further in vitro study reveals that aromatic‐turmerone‐targeted Toll‐like receptor 4 (TLR4) mediates downstream signaling and lowers the release of inflammatory mediators.