Investigation of mechanism of binding of molecular probe eosin to human serum albumin by Raman spectroscopy method

Investigation of mechanism of binding of molecular probe eosin to human serum albumin by Raman spectroscopy method

The mechanism of binding of molecular probe eosin to molecules of human serum albumin was studied by the Raman spectroscopy method. The position of binding center on human serum albumin molecule for eosin is determined. The amino acid residues of albumin molecule, participating in binding of eosin a...

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Veröffentlicht in:Laser physics letters 2007-05, Vol.4 (5), p.390-394
Hauptverfasser: Vlasova, I. M., Polyansky, D. V., Saletsky, A. M.
Format: Artikel
Sprache:eng
Schlagworte:
eosin
human serum albumin
protein binding centers
Raman spectroscopy
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Zusammenfassung:The mechanism of binding of molecular probe eosin to molecules of human serum albumin was studied by the Raman spectroscopy method. The position of binding center on human serum albumin molecule for eosin is determined. The amino acid residues of albumin molecule, participating in binding of eosin at different pH values of solution, are established. (© 2007 by Astro Ltd., Published exclusively by WILEY‐VCH Verlag GmbH & Co. KGaA)
ISSN:1612-2011
1612-202X
DOI:10.1002/lapl.200610112