Common duct stricture associated with hepatic artery infusion of FUDR

A case report is presented giving the first detailed description of a benign common duct stricture occurring in a patient receiving hepatic artery infusion of FUDR for metastatic colon cancer. It is postulated that the stricture results from a combination of drug toxicity, and hypoxemia of the duct,...

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Veröffentlicht in:Journal of surgical oncology 1986-01, Vol.31 (1), p.56-59
1. Verfasser: Laughlin, Edward H.
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description A case report is presented giving the first detailed description of a benign common duct stricture occurring in a patient receiving hepatic artery infusion of FUDR for metastatic colon cancer. It is postulated that the stricture results from a combination of drug toxicity, and hypoxemia of the duct, with the lesion occurring more often than is recognized. A guide is given for the evaluation of the FUDR‐infused patient with suspected nonmalignant duct stricture, and for the methods of alleviating extrahe‐patic blockage in these individuals.
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A guide is given for the evaluation of the FUDR‐infused patient with suspected nonmalignant duct stricture, and for the methods of alleviating extrahe‐patic blockage in these individuals.</description><identifier>ISSN: 0022-4790</identifier><identifier>EISSN: 1096-9098</identifier><identifier>DOI: 10.1002/jso.2930310113</identifier><identifier>PMID: 2935680</identifier><language>eng</language><publisher>New York: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Adenocarcinoma - drug therapy ; Adenocarcinoma - secondary ; Colonic Neoplasms - pathology ; Common Bile Duct Diseases - chemically induced ; common duct ; Constriction, Pathologic - chemically induced ; Floxuridine - administration &amp; dosage ; Floxuridine - adverse effects ; FUDR ; Hepatic Artery ; Humans ; infusion ; Infusions, Intra-Arterial - adverse effects ; Liver Neoplasms - drug therapy ; Liver Neoplasms - secondary ; Male ; Middle Aged ; stricture</subject><ispartof>Journal of surgical oncology, 1986-01, Vol.31 (1), p.56-59</ispartof><rights>Copyright © 1986 Wiley‐Liss, Inc., A Wiley Company</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3783-6e1615bf2853f0715ad81c4053d3ac85b7e29007e7331cd610263f4b98b7b26b3</citedby><cites>FETCH-LOGICAL-c3783-6e1615bf2853f0715ad81c4053d3ac85b7e29007e7331cd610263f4b98b7b26b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjso.2930310113$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjso.2930310113$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27903,27904,45553,45554</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2935680$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Laughlin, Edward H.</creatorcontrib><title>Common duct stricture associated with hepatic artery infusion of FUDR</title><title>Journal of surgical oncology</title><addtitle>J. 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subjects Adenocarcinoma - drug therapy
Adenocarcinoma - secondary
Colonic Neoplasms - pathology
Common Bile Duct Diseases - chemically induced
common duct
Constriction, Pathologic - chemically induced
Floxuridine - administration & dosage
Floxuridine - adverse effects
FUDR
Hepatic Artery
Humans
infusion
Infusions, Intra-Arterial - adverse effects
Liver Neoplasms - drug therapy
Liver Neoplasms - secondary
Male
Middle Aged
stricture
title Common duct stricture associated with hepatic artery infusion of FUDR
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