Common duct stricture associated with hepatic artery infusion of FUDR
A case report is presented giving the first detailed description of a benign common duct stricture occurring in a patient receiving hepatic artery infusion of FUDR for metastatic colon cancer. It is postulated that the stricture results from a combination of drug toxicity, and hypoxemia of the duct,...
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Veröffentlicht in: | Journal of surgical oncology 1986-01, Vol.31 (1), p.56-59 |
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description | A case report is presented giving the first detailed description of a benign common duct stricture occurring in a patient receiving hepatic artery infusion of FUDR for metastatic colon cancer. It is postulated that the stricture results from a combination of drug toxicity, and hypoxemia of the duct, with the lesion occurring more often than is recognized. A guide is given for the evaluation of the FUDR‐infused patient with suspected nonmalignant duct stricture, and for the methods of alleviating extrahe‐patic blockage in these individuals. |
doi_str_mv | 10.1002/jso.2930310113 |
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It is postulated that the stricture results from a combination of drug toxicity, and hypoxemia of the duct, with the lesion occurring more often than is recognized. A guide is given for the evaluation of the FUDR‐infused patient with suspected nonmalignant duct stricture, and for the methods of alleviating extrahe‐patic blockage in these individuals.</description><identifier>ISSN: 0022-4790</identifier><identifier>EISSN: 1096-9098</identifier><identifier>DOI: 10.1002/jso.2930310113</identifier><identifier>PMID: 2935680</identifier><language>eng</language><publisher>New York: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Adenocarcinoma - drug therapy ; Adenocarcinoma - secondary ; Colonic Neoplasms - pathology ; Common Bile Duct Diseases - chemically induced ; common duct ; Constriction, Pathologic - chemically induced ; Floxuridine - administration & dosage ; Floxuridine - adverse effects ; FUDR ; Hepatic Artery ; Humans ; infusion ; Infusions, Intra-Arterial - adverse effects ; Liver Neoplasms - drug therapy ; Liver Neoplasms - secondary ; Male ; Middle Aged ; stricture</subject><ispartof>Journal of surgical oncology, 1986-01, Vol.31 (1), p.56-59</ispartof><rights>Copyright © 1986 Wiley‐Liss, Inc., A Wiley Company</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3783-6e1615bf2853f0715ad81c4053d3ac85b7e29007e7331cd610263f4b98b7b26b3</citedby><cites>FETCH-LOGICAL-c3783-6e1615bf2853f0715ad81c4053d3ac85b7e29007e7331cd610263f4b98b7b26b3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjso.2930310113$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjso.2930310113$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27903,27904,45553,45554</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2935680$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Laughlin, Edward H.</creatorcontrib><title>Common duct stricture associated with hepatic artery infusion of FUDR</title><title>Journal of surgical oncology</title><addtitle>J. Surg. Oncol</addtitle><description>A case report is presented giving the first detailed description of a benign common duct stricture occurring in a patient receiving hepatic artery infusion of FUDR for metastatic colon cancer. It is postulated that the stricture results from a combination of drug toxicity, and hypoxemia of the duct, with the lesion occurring more often than is recognized. A guide is given for the evaluation of the FUDR‐infused patient with suspected nonmalignant duct stricture, and for the methods of alleviating extrahe‐patic blockage in these individuals.</description><subject>Adenocarcinoma - drug therapy</subject><subject>Adenocarcinoma - secondary</subject><subject>Colonic Neoplasms - pathology</subject><subject>Common Bile Duct Diseases - chemically induced</subject><subject>common duct</subject><subject>Constriction, Pathologic - chemically induced</subject><subject>Floxuridine - administration & dosage</subject><subject>Floxuridine - adverse effects</subject><subject>FUDR</subject><subject>Hepatic Artery</subject><subject>Humans</subject><subject>infusion</subject><subject>Infusions, Intra-Arterial - adverse effects</subject><subject>Liver Neoplasms - drug therapy</subject><subject>Liver Neoplasms - secondary</subject><subject>Male</subject><subject>Middle Aged</subject><subject>stricture</subject><issn>0022-4790</issn><issn>1096-9098</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE1PwkAYhDdGg4hevZn0DxTf7Xa_jgYFNY0YhXjcbLfbsAiU7LZB_r01JRhPnuYw80wyg9A1hiEGSG6XoRomkgDBgDE5QX0MksUSpDhF_TaQxCmXcI4uQlgCgJQs7aFeS1AmoI8eRtV6XW2iojF1FGrvTN14G-kQKuN0bYto5-pFtLBbXTsTaV9bv4_cpmyCa7GqjMbz-7dLdFbqVbBXBx2g-fhhNnqMs-nkaXSXxYZwQWJmMcM0LxNBSQkcU10IbFKgpCDaCJpzm0gAbjkh2BQMQ8JImeZS5DxPWE4GaNj1Gl-F4G2ptt6ttd8rDOrnDtXeoX7vaIGbDtg2-doWx_hhf-vLzt-5ld3_06ae36d_uuOOdaG2X0dW-0_FOOFUfbxMlKDZrB3zqjLyDRssedU</recordid><startdate>198601</startdate><enddate>198601</enddate><creator>Laughlin, Edward H.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>198601</creationdate><title>Common duct stricture associated with hepatic artery infusion of FUDR</title><author>Laughlin, Edward H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3783-6e1615bf2853f0715ad81c4053d3ac85b7e29007e7331cd610263f4b98b7b26b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>Adenocarcinoma - drug therapy</topic><topic>Adenocarcinoma - secondary</topic><topic>Colonic Neoplasms - pathology</topic><topic>Common Bile Duct Diseases - chemically induced</topic><topic>common duct</topic><topic>Constriction, Pathologic - chemically induced</topic><topic>Floxuridine - administration & dosage</topic><topic>Floxuridine - adverse effects</topic><topic>FUDR</topic><topic>Hepatic Artery</topic><topic>Humans</topic><topic>infusion</topic><topic>Infusions, Intra-Arterial - adverse effects</topic><topic>Liver Neoplasms - drug therapy</topic><topic>Liver Neoplasms - secondary</topic><topic>Male</topic><topic>Middle Aged</topic><topic>stricture</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Laughlin, Edward H.</creatorcontrib><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><jtitle>Journal of surgical oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Laughlin, Edward H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Common duct stricture associated with hepatic artery infusion of FUDR</atitle><jtitle>Journal of surgical oncology</jtitle><addtitle>J. Surg. Oncol</addtitle><date>1986-01</date><risdate>1986</risdate><volume>31</volume><issue>1</issue><spage>56</spage><epage>59</epage><pages>56-59</pages><issn>0022-4790</issn><eissn>1096-9098</eissn><abstract>A case report is presented giving the first detailed description of a benign common duct stricture occurring in a patient receiving hepatic artery infusion of FUDR for metastatic colon cancer. It is postulated that the stricture results from a combination of drug toxicity, and hypoxemia of the duct, with the lesion occurring more often than is recognized. A guide is given for the evaluation of the FUDR‐infused patient with suspected nonmalignant duct stricture, and for the methods of alleviating extrahe‐patic blockage in these individuals.</abstract><cop>New York</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>2935680</pmid><doi>10.1002/jso.2930310113</doi><tpages>4</tpages></addata></record> |
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source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
subjects | Adenocarcinoma - drug therapy Adenocarcinoma - secondary Colonic Neoplasms - pathology Common Bile Duct Diseases - chemically induced common duct Constriction, Pathologic - chemically induced Floxuridine - administration & dosage Floxuridine - adverse effects FUDR Hepatic Artery Humans infusion Infusions, Intra-Arterial - adverse effects Liver Neoplasms - drug therapy Liver Neoplasms - secondary Male Middle Aged stricture |
title | Common duct stricture associated with hepatic artery infusion of FUDR |
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