Intracavitary bleomycin for the control of malignant effusions

The results of treatment with intracavitary bleomycin are reported in twenty patients with a malignant pleural effusion and five patients with malignant ascites. The control rate was 17/20 (85%) patients with malignant pleural effusions and 3/5 (60%) patients with malignant ascites. Toxicities were...

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Veröffentlicht in:	Journal of surgical oncology 1981, Vol.16 (3), p.273-277
Hauptverfasser:	Bitran, Jacob D., Brown, Charles, Desser, Richard K., Kozloff, Mark F., Shapiro, Charles, Billings, Arthur A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Ascites bleomycin Bleomycin - administration & dosage Bleomycin - adverse effects effusion Female Fever - chemically induced Humans Male malignant effusion Middle Aged Peritoneal Neoplasms - drug therapy Pleural Effusion - drug therapy Pleural Neoplasms - drug therapy
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Zusammenfassung:	The results of treatment with intracavitary bleomycin are reported in twenty patients with a malignant pleural effusion and five patients with malignant ascites. The control rate was 17/20 (85%) patients with malignant pleural effusions and 3/5 (60%) patients with malignant ascites. Toxicities were minimal with fever being the most common side effect in four patients (16%). Bleomycin is an effective and nontoxic sclerosing agent.
ISSN:	0022-4790 1096-9098
DOI:	10.1002/jso.2930160312