A novel protocol for quantitative determination of 1,4‐dioxane in finished cleaning products

A novel protocol for quantitative determination of 1,4‐dioxane in finished cleaning products

A novel method to quantify 1,4‐dioxane in finished cleaning products using headspace gas chromatograph with mass spectrometry (HS GC/MS), single ion monitoring, and a fully deuterated internal standard has been developed. The method generates very linear calibration curves with a R2 of at least 0.99...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of surfactants and detergents 2023-07, Vol.26 (4), p.565-576
Hauptverfasser: Palumbo, Brian, Conrad‐Vlasak, Deena, Stanton, Kathleen
Format: Artikel
Sprache:eng
Schlagworte:
1,4‐dioxane
consumer products
ethoxylated surfactants
gas chromatograph
headspace
mass spectrometry
methodology
quantification
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A novel method to quantify 1,4‐dioxane in finished cleaning products using headspace gas chromatograph with mass spectrometry (HS GC/MS), single ion monitoring, and a fully deuterated internal standard has been developed. The method generates very linear calibration curves with a R2 of at least 0.99, excellent accuracy with spike/recovery of 97%–102%, and effective precision of 1%–7%RSD for different cleaning products. The method also produces an instrument limit of quantitation (LOQ) of
ISSN:1097-3958
1558-9293
DOI:10.1002/jsde.12674