Pyrexia in rabbits following the injection of filtrates of typical mold cultures

Filtrates of mold cultures representing 31 species which were propagated on a dextrose-peptone medium were injected intravenosly in rabbits. Significant elevations in body temperature varying over a wide range were observed for 16 of the 31 species. Pyrogen production appeared to be dependent upon t...

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Veröffentlicht in:Journal of the American Pharmaceutical Association (Scientific ed.) 1950-09, Vol.39 (9), p.502-504
Hauptverfasser: Harkness, William D., Loving, Walker L., Hodges, F.Allen
Format: Artikel
Sprache:eng
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Zusammenfassung:Filtrates of mold cultures representing 31 species which were propagated on a dextrose-peptone medium were injected intravenosly in rabbits. Significant elevations in body temperature varying over a wide range were observed for 16 of the 31 species. Pyrogen production appeared to be dependent upon the composition of the media.
ISSN:0095-9553
1930-2304
DOI:10.1002/jps.3030390908