Nitrites XIII. Sodium Theophylline Alkylglycollate Nitrate

Nitrites XIII. Sodium Theophylline Alkylglycollate Nitrate

A new solubilizing agent for theophylline is reported. Combinations of theophylline with isobutylglycollate nitrate are water soluble and produce slightly alkaline solutions. The depressor response of theophylline upon intravenous injection in the anesthetized dog is prolonged owing to the glycollat...

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Veröffentlicht in:Journal of the American Pharmaceutical Association (Scientific ed.) 1950-04, Vol.39 (4), p.221-222
Hauptverfasser: Iwamoto, Harry K., Bird, Joseph G., Carr, C. Jelleff, Harmon, John B., Krantz, John C.
Format: Artikel
Sprache:eng
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Zusammenfassung:A new solubilizing agent for theophylline is reported. Combinations of theophylline with isobutylglycollate nitrate are water soluble and produce slightly alkaline solutions. The depressor response of theophylline upon intravenous injection in the anesthetized dog is prolonged owing to the glycollate nitrate.
ISSN:0095-9553
1930-2304
DOI:10.1002/jps.3030390411